The Science

Built on decades of peptide research.

First identified in 1973, GHK-Cu is a naturally occurring copper-binding peptide studied for its role in skin biology. We’ve combined it with complementary peptides, barrier-supporting ingredients and hydrators in one thoughtfully formulated daily serum.

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Skin-X Clinical GHK-Cu Essential Serum 30 mL bottle

1973

GHK-Cu first identified

50+ years

of published research

4

peptides in one formula

0

added fragrance, oils or dyes

Our approach

The science behind every drop.

Every choice in the formula comes back to these three principles.

01.

Peptide Science

Our formula brings together GHK-Cu and complementary peptides to support smoother, firmer-looking skin.

02.

Barrier Support

Ectoin, Ceramide NP, Squalane and Panthenol help maintain hydration and support the skin barrier.

03.

Thoughtful Formulation

No added fragrance, essential oils or dyes. The serum’s distinctive blue colour comes from the copper peptide itself.

The science

Four peptides. One considered formula.

Discover the key ingredients behind our multi-peptide serum, formulated to support smoother-looking, hydrated and resilient skin.

  • Copper Tripeptide-1 (GHK-Cu)

    Copper Tripeptide-1 (GHK-Cu)

    A copper-binding peptide studied for its role in skin health and renewal.

  • Matrixyl® 3000

    Matrixyl® 3000

    (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7)

    A well-researched peptide complex that helps improve the appearance of fine lines and skin texture.

  • Ectoin

    Ectoin

    A protective molecule from extremophilic microorganisms that helps support hydration and the skin barrier.

  • Ceramide NP + Squalane

    Ceramide NP + Squalane

    Skin-identical lipids that replenish the barrier and help keep skin soft and supple.

  • Sodium Hyaluronate + Glycerin

    Sodium Hyaluronate + Glycerin

    Humectants that draw in and hold moisture for lasting hydration.

  • Panthenol (Pro-Vitamin B5) + Acetyl Glucosamine

    Panthenol (Pro-Vitamin B5) + Acetyl Glucosamine

    A soothing humectant and an amino sugar that helps support smoother, more even-looking skin.

4 Peptides

A targeted peptide complex for visible skin improvement.

Barrier Support

Helps maintain a healthy, resilient skin barrier.

Deep Hydration

Draws in and locks in moisture for plumper, smoother skin.

The serum’s blue colour comes from the copper peptide itself. No added fragrance, essential oils or dyes.

The texture

A silky serum that absorbs easily.

Apply 3 to 4 drops to clean face and neck, morning and evening.

References

The research behind our ingredients

These studies relate to individual ingredients, not to GHK-Cu Essential Serum as a finished product. Each study used its own concentration and test formula.

GHK-Cu

Pickart, Vasquez-Soltero & Margolina (2015), GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration, BioMed Research International. A review showing that GHK declines with age. In lab work it affects collagen and other skin-structure molecules, and in cosmetic products it was reported to improve the look of firmness, elasticity and fine lines.

Pickart & Margolina (2018), Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data, International Journal of Molecular Sciences. A review noting that GHK in the blood falls from about 200 ng/mL at age 20 to about 80 ng/mL by age 60, and discussing its use in skin and hair products.

Dou et al. (2020), The potential of GHK as an anti-aging peptide, Aging Pathobiology and Therapeutics. A review of research into GHK-Cu's anti-inflammatory and tissue remodelling activity.

Palmitoyl Pentapeptide-4

Robinson et al. (2005), Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin, International Journal of Cosmetic Science. A 12-week, double-blind, placebo-controlled split-face study in 93 women aged 35 to 55, which showed significant improvement in wrinkles and fine lines compared with placebo.

Matrixyl® 3000

Sederma (supplier), Matrixyl® 3000 technical data sheet. The supplier's 2-month test versus placebo showed reductions in the area of deep wrinkles and in wrinkle density. This is manufacturer data, not an independent study.

Ectoin

Kauth & Trusova (2022), Topical Ectoine Application in Children and Adults to Treat Inflammatory Diseases Associated with an Impaired Skin Barrier: A Systematic Review, Dermatology and Therapy. A review of six clinical studies, which found Ectoine formulas were safe and effective for impaired-barrier skin over up to 6 months.

One serum. Four peptides. A single daily step.

GHK-Cu Essential Serum 30mL · A$129 · Free tracked shipping Australia-wide

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